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Article

Association of chemokine receptor gene variants with HIV-1 genotype predicted tropism.

HIV medicine - 1 Nov 2014

Parczewski M, Urbańska A, Maciejewska K, Clark J, Leszczyszyn-Pynka M

Abstract excerpt

OBJECTIVES: As a switch from chemokine (C-C motif) receptor 5 [CCR5 (R5)] to chemokine (C-X-C motif) receptor 4 [CXCR4 (X4)] HIV-1 tropism is associated with symptomatic and AIDS stages of infection, while chemokine receptor gene variants modify the tempo of HIV disease progression, we aimed to analyse the association between pretreatment HIV-1 tropism and chemokine polymorphisms known to restrict disease...

Read the complete abstract on PubMed

Topics

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Share to CD4 Lymphocyte Count
Share to HIV-1
Share to HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Predictive Value of Tests

Share to Promoter Regions, Genetic

Share to Regression Analysis

Share to Viral Load

Share to Viral Tropism

Source

Identifiers

PMID: 24750723
DOI: 10.1111/hiv.12155

Genes

CCR5
CCR2
CXCR4

Variants

rs333
rs333

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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