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Article

HIV type 1 subtypes, coreceptor usage, and CCR5 polymorphism.

AIDS research and human retroviruses - 1 Nov 1997

Zhang L, Carruthers C D, He T, Huang Y, Cao Y, Wang G, Hahn B, Ho D D

Abstract excerpt

Identification of the chemokine receptors CCR5 and CXCR4 as the major coreceptors for HIV-1 entry has greatly assisted our understanding of HIV-1 pathogenesis, transmission, and tropism. However, most of our current knowledge on coreceptor usage comes from studies using HIV-1 strains or env genes...

Topics

Amino Acid Sequence
Geography
HIV-1
Humans
Molecular Sequence Data
Phenotype
Phylogeny
Polymorphism, Genetic
Receptors, CCR5
Receptors, CXCR4
Sequence Homology, Amino Acid
Serotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 9359654
DOI: 10.1089/aid.1997.13.1357

Genes

CCR5
CXCR4
CCR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9359654-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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