Article
HIV type 1 subtypes, coreceptor usage, and CCR5 polymorphism.
AIDS research and human retroviruses - 1 Nov 1997
Zhang L, Carruthers C D, He T, Huang Y, Cao Y, Wang G, Hahn B, Ho D D
Abstract excerpt
Identification of the chemokine receptors CCR5 and CXCR4 as the major coreceptors for HIV-1 entry has greatly assisted our understanding of HIV-1 pathogenesis, transmission, and tropism. However, most of our current knowledge on coreceptor usage comes from studies using HIV-1 strains or env genes derived from the genetic subtype B predominant in North America and western Europe. In this report, the coreceptor...
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