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Article

CXCR4 expression accounts for clinical phenotype and outcome in acute myeloid leukemia.

Cytometry. Part B, Clinical cytometry - 1 Sept 2014

Mannelli Francesco, Cutini Ilaria, Gianfaldoni Giacomo, Bencini Sara, Scappini Barbara, Pancani Fabiana, Ponziani Vanessa, Bonetti Maria Ida, Biagiotti Caterina, Longo Giovanni, Bosi Alberto

Abstract excerpt

BACKGROUND: In acute myeloid leukemia (AML), CXCR4 expression has been correlated with leukocytosis and prognosis. METHODS: We quantified CXCR4 expression by flow cytometry on leukemic cells in 142 AML patients. RESULTS: We confirm a correlation between high CXCR4 expression and leukemic burden. Furthermore, we documented a correlation with platelet count, dysplastic megakaryopoiesis, hepato-splenomegaly and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24500843
DOI: 10.1002/cyto.b.21156

Genes

CXCR4
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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