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Article

The role of CXCR4 in highly malignant human gliomas biology: Current knowledge and future directions

8 Apr 2014

Abstract excerpt

Given the extensive histomorphological heterogeneity of high-grade gliomas, in terms of extent of invasiveness, angiogenesis, and necrosis and the poor prognosis for patients despite the advancements made in therapeutic management. The identification of genes associated with these phenotypes will permit a better definition of glioma heterogeneity, which may ultimately lead to better treatment strategies. CXCR4, a...

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PMID: 24715652
DOI: 10.1002/glia.22669

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