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Article

Longer telomeres are associated with cancer risk in MMR-proficient hereditary non-polyposis colorectal cancer.

PloS one - 1 Jan 2014

Seguí Nuria, Guinó Elisabet, Pineda Marta, Navarro Matilde, Bellido Fernando, Lázaro Conxi, Blanco Ignacio, Moreno Victor, Capellá Gabriel, Valle Laura

Abstract excerpt

Aberrant telomere length measured in blood has been associated with increased risk of several cancer types. In the field of hereditary non-polyposis colorectal cancer (CRC), and more particularly in Lynch syndrome, caused by germline mutations in the mismatch repair (MMR) genes, we recently found that cancer-affected MMR gene mutation carriers had shorter telomeres and more pronounced shortening of telomere...

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Share to Colorectal Neoplasms, Hereditary Nonpolyposis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24498269
DOI: 10.1371/journal.pone.0086063
PMCID: PMC3911901

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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