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Article

Genetic variant in the telomerase gene modifies cancer risk in Lynch syndrome.

European journal of human genetics : EJHG - 1 May 2013

Bellido Fernando, Guinó Elisabet, Jagmohan-Changur Shantie, Seguí Nuria, Pineda Marta, Navarro Matilde, Lázaro Conxi, Blanco Ignacio, Vasen Hans F A, Moreno Victor, Capellá Gabriel, Wijnen Juul T, Valle Laura

Abstract excerpt

Lynch syndrome (LS) is an inherited cancer-predisposing disorder caused by germline mutations in the mismatch repair (MMR) genes. The high variability in individual cancer risk observed among LS patients suggests the existence of modifying factors. Identifying genetic modifiers of risk could help...

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Identifiers

PMID: 22948024
DOI: 10.1038/ejhg.2012.204
PMCID: PMC3641380

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22948024-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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