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Article

Measurement of Telomere Length in Colorectal Cancers for Improved Molecular Diagnosis.

International journal of molecular sciences - 29 Aug 2017

Balc'h Eric Le, Grandin Nathalie, Demattei Marie-Véronique, Guyétant Serge, Tallet Anne, Pagès Jean-Christophe, Ouaissi Mehdi, Lecomte Thierry, Charbonneau Michel

Abstract excerpt

All tumors have in common to reactivate a telomere maintenance mechanism to allow for unlimited proliferation. On the other hand, genetic instability found in some tumors can result from the loss of telomeres. Here, we measured telomere length in colorectal cancers (CRCs) using TRF (Telomere Restriction Fragment) analysis. Telomeric DNA content was also quantified as the ratio of total telomeric (TTAGGG)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28850092
DOI: 10.3390/ijms18091871
PMCID: PMC5618520

Genes

BRAF
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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