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Relationship of telomere length in colorectal cancer patients with cancer phenotype and patient prognosis

16 Jul 2019

Abstract excerpt

BACKGROUND: Telomeres, repetitive DNA capping ends of eukaryotic chromosomes, are important in the maintenance of genomic integrity. Perturbed telomeres are common features of many human malignancies, including colorectal cancer. METHODS: Telomere length (TL), measured by a Monochrome Multiplex Real-Time qPCR, was investigated in tumour tissues, adjacent mucosa, and blood from patients with colorectal cancer with...

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PMID: 31312029
DOI: 10.1038/s41416-019-0525-3

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