Article
Telomere length in peripheral blood cells of germline TP53 mutation carriers is shorter than that of normal individuals of corresponding age.
Cancer - 1 Aug 2007
Trkova Marie, Prochazkova Kamila, Krutilkova Vera, Sumerauer David, Sedlacek Zdenek
Abstract excerpt
BACKGROUND: A decrease in the age at cancer onset and increase in cancer incidence in successive generations in Li-Fraumeni syndrome (LFS) families with germline TP53 mutations have been previously described. In the current study a possible relation was analyzed between telomere length and cancer...
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