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Article

Three new genetic loci (R1210C in CFH, variants in COL8A1 and RAD51B) are independently related to progression to advanced macular degeneration.

PloS one - 1 Jan 2014

Seddon Johanna M, Reynolds Robyn, Yu Yi, Rosner Bernard

Abstract excerpt

OBJECTIVES: To assess the independent impact of new genetic variants on conversion to advanced stages of AMD, controlling for established risk factors, and to determine the contribution of genes in predictive models. METHODS: In this prospective longitudinal study of 2765 individuals, 777 subject...

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Identifiers

PMID: 24498017
DOI: 10.1371/journal.pone.0087047
PMCID: PMC3909074

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24498017-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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