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Article

Prediction model for prevalence and incidence of advanced age-related macular degeneration based on genetic, demographic, and environmental variables.

Investigative ophthalmology & visual science - 1 May 2009

Seddon Johanna M, Reynolds Robyn, Maller Julian, Fagerness Jesen A, Daly Mark J, Rosner Bernard

Abstract excerpt

PURPOSE: The joint effects of genetic, ocular, and environmental variables were evaluated and predictive models for prevalence and incidence of AMD were assessed. METHODS: Participants in the multicenter Age-Related Eye Disease Study (AREDS) were included in a prospective evaluation of 1446 individuals, of which 279 progressed to advanced AMD (geographic atrophy or neovascular disease) and 1167 did not progress...

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Source

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Identifiers

PMID: 19117936
DOI: 10.1167/iovs.08-3064
PMCID: PMC3772781

Genes

CFB
CFH
ARMS2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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