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Article

Risk models for progression to advanced age-related macular degeneration using demographic, environmental, genetic, and ocular factors.

Ophthalmology - 1 Nov 2011

Seddon Johanna M, Reynolds Robyn, Yu Yi, Daly Mark J, Rosner Bernard

Abstract excerpt

PURPOSE: To expand our predictive models for progression to advanced stages of age-related macular degeneration (AMD) based on demographic, environmental, genetic, and ocular factors, using longer follow-up, time varying analyses, calculation of absolute risks, adjustment for competing risks, and detailed baseline AMD and drusen status. DESIGN: Prospective, longitudinal study. PARTICIPANTS: We included 2937...

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Identifiers

PMID: 21959373
DOI: 10.1016/j.ophtha.2011.04.029
PMCID: PMC4097877

Genes

ARMS2
CFB
CFH
HTRA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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