Article
Functional mutations in and characterization of VHH against Helicobacter pylori urease.
Applied biochemistry and biotechnology - 1 Mar 2014
Hoseinpoor Reyhaneh, Mousavi Gargari Seyed Latif, Rasooli Iraj, Rajabibazl Masoumeh, Shahi Bahareh
Abstract excerpt
Manipulation of clinically significant antibodies can effectively improve the processes of diagnosis and treatment. Affinity maturation process has a significant role in improvement of antibodies efficiency. Error-prone PCR technique is one of the proposed methods for improvement of the affinity of antibodies. In the present research, a method was applied to camel heavy-chain antibody (VHH, nanobody) raised...
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