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Characterization of novel CD19-specific VHHs isolated from a camelid immune library by phage display

8 Dec 2023

Abstract excerpt

Abstract Background Monoclonal antibody (mAb)-based immunotherapies have achieved promising outcomes in the treatment of immunological and oncological indications. CD19 is considered one of the most qualified antigens in the treatment of B-cell neoplasms. VHHs (nanobodies) are known for their physicochemical advantages over conventional mAbs rendering them suitable therapeutics and diagnostic tools. Herein, we...

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PMID: 38066569
DOI: 10.1186/s12967-023-04524-6

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