Article

ModiBodies: A computational method for modifying nanobodies to improve their antigen binding affinity and specificity

2019-10-28

Abstract excerpt

Nanobodies are special derivatives of antibodies, which consist of only a single chain. Their hydrophilic side prevents them from having the solubility and aggregation problems of conventional antibodies, and they retain the similar size and affinity of the binding area to the antigen. Nanobodies have become of considerable interest for next-generation biotechnological tools for antigen recognition. They can be ea...

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Literature Corpus work: 4927ab54-2c72-5f63-bac3-f6a2d97b68d8
DOI: 10.1101/820373

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