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Article

Tryptophan hydroxylase 2 (TPH2) gene polymorphisms and psychiatric comorbidities in temporal lobe epilepsy.

Epilepsy & behavior : E&B - 1 Mar 2014

Bragatti José Augusto, Bandeira Isabel Cristina, de Carvalho Agata Mantese, Abujamra Ana Lúcia, Leistner-Segal Sandra, Bianchin Marino Muxfeldt

Abstract excerpt

Psychiatric comorbidities are frequent in temporal lobe epilepsy (TLE). It is plausible that variance in serotonin-related genes is involved in the susceptibility of these associations. We report here the results on the association of tryptophan hydroxylase 2 (TPH2) gene polymorphisms with psychiatric comorbidities in TLE. A cohort study was conducted on 163 patients with TLE. We assessed the influence of the...

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Source

Identifiers

PMID: 24491795
DOI: 10.1016/j.yebeh.2014.01.007

Genes

TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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