Article
Association study of functional polymorphisms in serotonin transporter gene with temporal lobe epilepsy in Han Chinese population.
European journal of neurology - 1 Feb 2012
Li J, Lin H, Zhu X, Li L, Wang X, Sun W, Wu X, Liu A, Niu F, Wang Y, Liu Y
Abstract excerpt
BACKGROUND AND PURPOSE: Serotoninergic dysfunction was reported to be involved in aetiology of temporal lobe epilepsy (TLE). Serotonin (5-HT) is actively cleared from synaptic cleft by serotonin transporter (5-HTT). We investigated the association between three common polymorphisms of 5-HTT gene, which may influence gene expression or function, and risk for TLE. METHODS: Three hundred and thirty-four patients...
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