Article
Serotonin transporter (5-HTT) gene polymorphisms and susceptibility to epilepsy: a meta-analysis and meta-regression.
Genetic testing and molecular biomarkers - 1 Dec 2013
Yang Kang, Su Jing, Hu Zengchun, Lang Rui, Sun Xu, Li Xinyu, Wang Dong, Wei Minghai, Yin Jian
Abstract excerpt
AIMS: Serotonin transporter (5-HTT) plays a central role in the regulation of serotonin (5-hydroxytryptamine [5-HT]) synaptic function. Disturbances in 5-HT transmission are the most frequently reported neurobiological substrates of suicidal behavior. Emerging evidence has shown that the common polymorphisms in the 5-HTT gene may contribute to the risk of epilepsy, but individually published studies showed...
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