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Lowered Paraoxonase 1 Activities May Explain the Comorbidities Between Temporal Lobe Epilepsy or Mesial Temporal Sclerosis and Comorbid Depression, Anxiety and Psychosis

2020-03-19

Abstract excerpt

<h4>Background: </h4> Temporal lobe epilepsy (TLE) is the most common focal epilepsy subtype in adults and is frequently accompanied by depression, anxiety and psychosis. Aberrations in total paraoxonase (PON)1 status may occur in TLE and those psychiatric conditions. <h4>Methods:</h4> We examined paraoxonase (PON)1 status, namely Q192R PON1 genotypes and PON1 enzymatic activities, in 40 normal controls and 104 TL...

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Literature Corpus work
31e06153-4cbc-5657-b495-e3b73faa4fca
DOI
10.20944/preprints202003.0292.v1
Open publication

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