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Article

Tyrosine receptor kinase B gene variants (NTRK2 variants) are associated with depressive disorders in temporal lobe epilepsy.

Epilepsy & behavior : E&B - 1 Jun 2017

Torres Carolina Machado, Siebert Marina, Bock Hugo, Mota Suelen Mandelli, Castan Juliana Unis, Scornavacca Francisco, de Castro Luiza Amaral, Saraiva-Pereira Maria Luiza, Bianchin Marino Muxfeldt

Abstract excerpt

RATIONALE: Psychiatric comorbidities are highly prevalent in epilepsy, adding an important burden to the disease and profoundly affecting the quality of life of these individuals. Patients with temporal lobe epilepsy (TLE) are especially at risk to develop depression and several lines of evidence suggest that the association of depression with epilepsy might be related to common biological substrates. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28550723
DOI: 10.1016/j.yebeh.2017.03.030

Genes

NTRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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