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Article

SLC6A4 gene variants and temporal lobe epilepsy susceptibility: a meta-analysis.

Molecular biology reports - 1 Dec 2012

Córdoba Marta, Consalvo Damián, Moron Dolores Gonzalez, Kochen Silvia, Kauffman Marcelo Andrés

Abstract excerpt

There seems to be a role for serotoninergic neuro-transmission in the pathophysiology of the epilepsies. Different groups have studied the role of regulatory variants in the SLC6A4 gene, which code for the central serotonin transporter, in the complex genetics of temporal lobe epilepsy (TLE) obtaining contradictory findings. Therefore, a systematic review and critical analysis of this topic seem to be timely....

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PMID: 23065262
DOI: 10.1007/s11033-012-1949-5

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