Involvement of tryptophan hydroxylase 2 gene polymorphisms in susceptibility to tic disorder in Chinese Han population.

doi:10.1186/1744-9081-9-6

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Article

Involvement of tryptophan hydroxylase 2 gene polymorphisms in susceptibility to tic disorder in Chinese Han population.

Behavioral and brain functions : BBF - 29 Jan 2013

Zheng Ping, Li Erzhen, Wang Jianhua, Cui Xiaodai, Wang Liwen

Abstract excerpt

BACKGROUND: Tryptophan hydroxylase-2 (TPH2) is a potential candidate gene for screening tic disorder (TD). METHODS: A case-control study was performed to examine the association between the TPH2 gene and TD. The Sequenom® Mass ARRAY iPLEX GOLD System was used to genotype two single nucleotide polymorphisms (SNPs) of the TPH2 gene in 149 TD children and in 125 normal controls. RESULTS: For rs4565946, individuals...

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PMID: 23360517
DOI: 10.1186/1744-9081-9-6
PMCID: PMC3573945

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TPH2

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