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Article

Polymorphisms assessment in the promoter region of IL12RB2 in Amazon leprosy patients.

Human immunology - 1 Jun 2014

Silva G A V, Santos M P, Motta-Passos I, Boechat A L, Malheiro A, Ramasawmy R, Naveca F G, de Paula L

Abstract excerpt

Leprosy displays a wide clinical spectrum that is dependent of the type of immune response. We investigate here whether polymorphisms in the promoter region of the IL12RB2 gene are associated with susceptibility or resistance to clinical forms of leprosy. Nucleotide sequencing of the promoter region of IL12RB2 encompassing SNPs -1035 A/G, -1033 T/C, -1023 A/G, -650 del/G and -464 A/G was performed on DNA samples...

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PMID: 24486579
DOI: 10.1016/j.humimm.2014.01.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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