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Article

IFN-γ +875 microsatellite polymorphism as a potential protection marker for leprosy patients from Amazonas state, Brazil.

Cytokine - 1 Nov 2012

Silva G A V, Santos M P, Mota-Passos I, Boechat A L, Malheiro A, Naveca F G, de Paula L

Abstract excerpt

Polymorphisms present in the first intron of IFN-γ may have an important role in the regulation of the immune response, which could have functional consequences for gene transcription. Leprosy patients are characterized by different immune responses in different clinical forms. We investigated a possible association of the +874 polymorphism and CA repeats present in the first intron of IFN-γ with susceptibility...

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PMID: 22683002
DOI: 10.1016/j.cyto.2012.04.043

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IFN-γ +875 microsatellite polymorphism as a potential protection marker for leprosy patients from Amazonas state, Brazil.PMID 22683002Read ↗

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