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Article

IL-10 promoter single nucleotide polymorphisms are significantly associated with resistance to leprosy.

Human genetics - 1 Nov 2005

Malhotra Dheeraj, Darvishi Katayoon, Sood Soni, Sharma Swarkar, Grover Chander, Relhan Vineet, Reddy B S N, Bamezai R N K

Abstract excerpt

The minor haplotype -3575A/-2849G/-2763C in IL-10 promoter has been defined as a marker of disease resistance to leprosy and its severity in Brazilian population. Our investigation of six single-nucleotide polymorphisms (SNPs) in IL-10 promoter in 282 Indian leprosy patients and 266 healthy controls by direct PCR sequencing, however, showed that the extended haplotype: -3575T/-2849G/-2763C/-1082A/-819C/-592C was...

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Identifiers

PMID: 16163478
DOI: 10.1007/s00439-005-0042-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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