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Article

Polymorphisms in the 5' flanking region of IL12RB2 are associated with susceptibility to periodontal diseases in the Japanese population.

Journal of clinical periodontology - 1 Apr 2008

Takeuchi-Hatanaka Kazu, Ohyama Hideki, Nishimura Fusanori, Kato-Kogoe Nahoko, Soga Yoshihiko, Matsushita Sho, Nakasho Keiji, Yamanegi Koji, Yamada Naoko, Terada Nobuyuki, Takashiba Shogo

Abstract excerpt

OBJECTIVES: The expression of interleukin (IL)-12Rbeta2 molecule is a crucial regulatory factor in the T-helper type (Th) 1 differentiation of T cells. To elucidate the role of the cell-mediated immune (CMI) response in the pathogenesis of periodontitis, Japanese periodontal patients were subject...

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Identifiers

PMID: 18353079
DOI: 10.1111/j.1600-051X.2008.01208.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18353079-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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