Article
Association of variants in the IL12B gene with leprosy and tuberculosis.
Tissue antigens - 1 Apr 2007
Morahan G, Kaur G, Singh M, Rapthap C C, Kumar N, Katoch K, Mehra N K, Huang D
Abstract excerpt
There is a great range in outcomes after mycobacterial infections, and this is probably due to individual variation in immune responses. One of the key cytokine regulators of the immune response is interleukin (IL-) 12. The IL12B gene encodes the p40 chain of both IL-12 and IL-23 and it has two m...
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