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Article

Fc gamma RIIB activation leads to inhibition of signalling by independently ligated receptors.

Biochemical Society transactions - 1 Feb 2003

Brauweiler A M, Cambier J C

Abstract excerpt

The inhibitory IgG receptor, Fc gamma RIIB, blocks signalling by co-aggregated antigen receptors on mature and activated B-cells. Fc gamma RIIB is also expressed by immature B-cells; however, its function on these cells has not been defined. In the present paper, we demonstrate that immature B-cells are highly sensitive to inhibitory signalling mediated by Fc gamma RIIB. Co-aggregation of Fc gamma RIIB with the...

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Source

Identifiers

PMID: 12546702
DOI: 10.1042/bst0310281

Genes

BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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