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Article

Negative regulation of mast cell proliferation by FcgammaRIIB.

Molecular immunology - 1 Sept 2002

Malbec Odile, Attal Jean-Pierre, Fridman Wolf H, Daëron Marc

Abstract excerpt

FcgammaRIIB are single-chain low-affinity receptors for the Fc portion of IgG antibodies that are widely expressed by hematopoietic cells including mast cells. We previously demonstrated that FcgammaRIIB negatively regulate cell activation triggered by receptors that possess Immunoreceptor Tyrosine-based Activation Motifs (ITAMs) including high-affinity IgE receptors (FcepsilonRI). FcgammaRIIB possess an...

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PMID: 12217398
DOI: 10.1016/s0161-5890(02)00078-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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