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Article

Association of p56lck with IL-2 receptor beta chain is critical for the IL-2-induced activation of p56lck.

The EMBO journal - 1 Feb 1993

Minami Y, Kono T, Yamada K, Kobayashi N, Kawahara A, Perlmutter R M, Taniguchi T

Abstract excerpt

Previous studies demonstrate that p56lck, a member of the src-family of protein tyrosine kinases (PTKs), can physically associate with the interleukin-2 (IL-2) receptor beta chain (IL-2R beta) and that IL-2 receptor engagement stimulates p56lck activity. To examine the mechanisms underlying p56lck PTK activation by IL-2, we established a mouse pro-B cell line, BAF-B03, expressing both IL-2R beta (either the...

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Identifiers

PMID: 8440263
DOI: 10.1002/j.1460-2075.1993.tb05710.x
PMCID: PMC413263

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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