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Article

A polymorphism in the promoter region of the selenoprotein S gene (SEPS1) contributes to Hashimoto's thyroiditis susceptibility.

The Journal of clinical endocrinology and metabolism - 1 Apr 2014

Santos Liliana R, Durães Cecília, Mendes Adélia, Prazeres Hugo, Alvelos Maria Inês, Moreira Carla Susete, Canedo Paulo, Esteves César, Neves Celestino, Carvalho Davide, Sobrinho-Simões Manuel, Soares Paula

Abstract excerpt

CONTEXT: The association between selenium and inflammation and the relevance of selenoproteins in follicular thyroid cell physiology have pointed to a putative role of selenoproteins in the pathogenesis of autoimmune thyroid diseases. OBJECTIVE: The aim of this study was to evaluate the role of a promoter variation in SEPS1, the selenoprotein S gene, in the risk for developing Hashimoto's thyroiditis (HT)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24471570
DOI: 10.1210/jc.2013-3539

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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