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Article

Variation in the selenoprotein S gene locus is associated with coronary heart disease and ischemic stroke in two independent Finnish cohorts.

Human genetics - 1 Nov 2007

Alanne Mervi, Kristiansson Kati, Auro Kirsi, Silander Kaisa, Kuulasmaa Kari, Peltonen Leena, Salomaa Veikko, Perola Markus

Abstract excerpt

Selenoprotein S (SEPS1) is a novel candidate gene involved in the regulation of inflammatory response and protection from oxidative damage. This study explored the genetic variation in the SEPS1 locus for an association with CVD as well as with quantitative phenotypes related to obesity and inflammation. We used the case-cohort design and time-to-event analysis in two separate prospectively followed...

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Identifiers

PMID: 17641917
DOI: 10.1007/s00439-007-0402-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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