Article
A case-control study of selenoprotein genes polymorphisms and autoimmune thyroid diseases in a Chinese population.
BMC medical genetics - 12 May 2017
Xiao Ling, Yuan Jianghong, Yao Qiuming, Yan Ni, Song Ronghua, Jiang Wenjuan, Li Danfeng, Shi Liangfeng, Zhang Jin-An
Abstract excerpt
BACKGROUND: Selenium is an essential trace and there is a high selenium concentration in the thyroid gland. Selenium deficiency may impair the thyroid function. The aim of this study was to investigate the association between three selenoprotein genes polymorphisms and autoimmune thyroid diseases. METHODS: We genotyped six single-nucleotide polymorphisms (SNPs), rs6865453 in selenoprotein P gene (SELENOP),...
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