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Article

Evaluation of the Variability in Selenoprotein Genes in Hepatocellular Carcinoma Patients.

Biochemical genetics - 1 Jun 2026

de Freitas Alves Andressa, Baldissera Vanessa Dido, da Rocha Tatiane Jacobsen, Cerski Carlos Thadeu Schmidt, Fontes Paulo Ott, Giovenardi Márcia, Fiegenbaum Marilu, Almeida Silvana

Abstract excerpt

Hepatocarcinogenesis is associated with various factors, including oxidative stress. Alterations in selenoprotein genes could impair redox balance and influence cancer development. In this study, we aimed to evaluate the association of single nucleotide variants (SNVs) from selenoproteins with hepatocellular carcinoma risk. The case and healthy groups were genotyped using quantitative polymerase chain reaction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40794213
DOI: 10.1007/s10528-025-11220-1

Genes

GPX1
SELENOP
GPX4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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