Article
A CARD9 polymorphism is associated with decreased likelihood of persistent conjugated hyperbilirubinemia in intestinal failure.
PloS one - 1 Jan 2014
Burghardt Karolina Maria, Avinashi Vishal, Kosar Christina, Xu Wei, Wales Paul W, Avitzur Yaron, Muise Aleixo
Abstract excerpt
Recently, genetic associations have been described in intestinal transplants. Namely, Crohn's disease susceptibility gene NOD2 polymorphisms have been reported to be more prevalent in patients with graft failure following intestinal transplantation (IT). Therefore, we sought to determine if polymorphisms in the NOD2 signaling cascade, including NOD2, CARD9, RAC1 and ATG16L1 are associated with intestinal failure...
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