Article
The role Of CARD9 in the pathogensis of IgA nephropathy
2019-01-01
Abstract excerpt
IgA nephropathy (IgAN) is a common cause of primary glomerulonephritis worldwide. It is characterised by the deposition of poorly galactosylated IgA1 immune complexes in the renal mesangium, leading to end stage renal damage in 30% of patients. At present, the pathogenesis of IgAN is not well understood. IgAN GWAS studies revealed an association between IgAN and a SNP within the coding sequence of the CARD9 gene....
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Identifiers and source
- Literature Corpus work
- 6aecd26a-a74b-5806-ae2b-a4e82fadd8d7
- DOI
- 10.25392/leicester.data.11108711.v1