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Article

NOD2 mutations are associated with the development of intestinal failure in the absence of Crohn's disease.

Clinical nutrition (Edinburgh, Scotland) - 1 Dec 2013

Schäffler Holger, Schneider Nina, Hsieh Chih-Jen, Reiner Johannes, Nadalin Silvio, Witte Maria, Königsrainer Alfred, Blumenstock Gunnar, Lamprecht Georg

Abstract excerpt

BACKGROUND & AIMS: Short bowel syndrome (SBS) and intestinal failure (IF) are multi-factorial conditions which in adults result from extensive intestinal resection. NOD2 is an intracellular pattern recognition receptor associated with CD. An unexpected high frequency of NOD2 mutations has been found in patients undergoing intestinal transplantation (35%). The role of NOD2 in a cohort with SBS/IF not specifically...

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Source

Identifiers

PMID: 23562557
DOI: 10.1016/j.clnu.2013.02.014

Genes

NOD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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