Article
Nucleotide oligomerization domain 2 polymorphisms in patients with intestinal failure.
Journal of gastroenterology and hepatology - 1 Feb 2013
Guerra Juan Francisco, Zasloff Michael, Lough Denver, Abdo Joseph, Hawksworth Jason, Mastumoto Cal, Girlanda Raffaele, Island Eddie, Shetty Kirty, Kaufman Stuart, Fishbein Thomas
Abstract excerpt
BACKGROUND: Nucleotide oligomerization domain 2 (NOD2) has been associated with intestinal immunity after the discovery that its polymorphisms are linked to Crohn's disease (CD). Intestinal failure (IF) represents a wider spectrum of diseases where intestinal homeostasis has been disrupted. AIM: To evaluate the prevalence of NOD2 mutations in a population with IF as well as its association with the different...
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