Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae.

PloS one - 1 Jan 2012

Zhang Jing, Silao Fitz Gerald S, Bigol Ursela G, Bungay Alice Alma C, Nicolas Marilou G, Heitman Joseph, Chen Ying-Lien

Abstract excerpt

Candida lusitaniae is an emerging fungal pathogen that infects immunocompromised patients including HIV/AIDS, cancer, and neonatal pediatric patients. Though less prevalent than other Candida species, C. lusitaniae is unique in its ability to develop resistance to amphotericin B. We investigated the role of the calcium-activated protein phosphatase calcineurin in several virulence attributes of C. lusitaniae...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcineurin
Share to Calcineurin Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Caspofungin

Share to Echinocandins

Share to Hyphae

Share to Keratitis

Share to Lipopeptides

Source

Open in PubMed Open full text

Identifiers

PMID: 22952924
DOI: 10.1371/journal.pone.0044192
PMCID: PMC3432075

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcineurin is required for pseudohyphal growth, virulence, and drug resistance in Candida lusitaniae.PMID 22952924Read ↗

Calcineurin Controls Hyphal Growth, Virulence, and Drug Tolerance of Candida tropicalisSemantic proximity Read ↗

The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida aurisSemantic proximity Read ↗

Calcineurin Orchestrates Hyphal Growth, Septation, Drug Resistance and Pathogenesis of Aspergillus fumigatus: Where Do We Go from Here?Semantic proximity Read ↗

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in<i>Candida glabrata</i>Semantic proximity Read ↗

Calcineurin is essential for Candida albicans survival in serum and virulence.Semantic proximity Read ↗

Calcineurin as a multifunctional regulator: Unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesisSemantic proximity Read ↗

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.Semantic proximity Read ↗

Calcineurin-dependent contributions to fitness in the opportunistic pathogen Candida glabrataSemantic proximity Read ↗

Linking Cellular Morphogenesis with Antifungal Treatment and Susceptibility in Candida PathogensSemantic proximity Read ↗

Calcineurin orchestrates dimorphic transitions, antifungal drug responses and host-pathogen interactions of the pathogenic mucoralean fungus Mucor circinelloides.Semantic proximity Read ↗

Signaling pathways governing the pathobiological features and antifungal drug resistance of Candida aurisSemantic proximity Read ↗

Regulatory Circuitry Governing Fungal Development, Drug Resistance, and DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.