Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.

Fungal genetics and biology : FG & B - 1 Feb 2010

Reedy Jennifer L, Filler Scott G, Heitman Joseph

Abstract excerpt

The protein phosphatase calcineurin is a key mediator of virulence and antifungal susceptibility of multiple fungal pathogens including Candida albicans, Cryptococcus neoformans, and Aspergillus fumigatus, and has clinical potential as a therapeutic target to increase the efficacy of the current antifungal armamentarium. Despite the importance of this signaling pathway, few components of the calcineurin-signaling...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antifungal Agents
Share to Calcineurin
Share to Candida albicans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Candidiasis

Share to Fluconazole

Share to Lithium Chloride

Share to Mice, Inbred ICR

Share to Sodium Dodecyl Sulfate

Source

Open in PubMed Open full text

Identifiers

PMID: 19755168
DOI: 10.1016/j.fgb.2009.09.002
PMCID: PMC2815136

Genes

MID1
RCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Elucidating the Candida albicans calcineurin signaling cascade controlling stress response and virulence.PMID 19755168Read ↗

Convergent Evolution of Calcineurin Pathway Roles in Thermotolerance and Virulence in<i>Candida glabrata</i>Semantic proximity Read ↗

Calcineurin Controls Hyphal Growth, Virulence, and Drug Tolerance of Candida tropicalisSemantic proximity Read ↗

Calcineurin is essential for Candida albicans survival in serum and virulence.Semantic proximity Read ↗

The calcineurin pathway regulates extreme thermotolerance, cell membrane and wall integrity, antifungal resistance, and virulence in Candida aurisSemantic proximity Read ↗

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.Semantic proximity Read ↗

CRZ1, a target of the calcineurin pathway in Candida albicans.Semantic proximity Read ↗

Calcineurin as a multifunctional regulator: Unraveling novel functions in fungal stress responses, hyphal growth, drug resistance, and pathogenesisSemantic proximity Read ↗

Dissecting the Roles of the Calcineurin Pathway in Unisexual Reproduction, Stress Responses, and Virulence in Cryptococcus deneoformans.Semantic proximity Read ↗

Calcineurin-dependent contributions to fitness in the opportunistic pathogen Candida glabrataSemantic proximity Read ↗

The tricarboxylic acid cycle, cell wall integrity pathway, cytokinesis and intracellular pH homeostasis are involved in the sensitivity of Candida albicans cells to high levels of extracellular calcium.Semantic proximity Read ↗

The involvement of the Mid1/Cch1/Yvc1 calcium channels in Aspergillus fumigatus virulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.