Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of neuregulin 3 genotype on human prefrontal cortex physiology.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Jan 2014

Tost Heike, Callicott Joseph H, Rasetti Roberta, Vakkalanka Radhakrishna, Mattay Venkata S, Weinberger Daniel R, Law Amanda J

Abstract excerpt

The neuregulin 3 gene (NRG3) plays pleiotropic roles in neurodevelopment and is a putative susceptibility locus for schizophrenia. Specifically, the T allele of NRG3 rs10748842 has been associated with illness risk, altered cognitive function, and the expression of a novel splice isoform in prefrontal cortex (PFC), but the neural system effects are unexplored. Here, we report an association between rs10748842 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype
Share to Neuregulins
Share to Photic Stimulation
Share to Prefrontal Cortex
Share to Psychomotor Performance
Share to Risk
Share to Schizophrenia
Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24431462
DOI: 10.1523/JNEUROSCI.3496-13.2014
PMCID: PMC3891948

Genes

NRG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of neuregulin 3 genotype on human prefrontal cortex physiology.PMID 24431462Read ↗

Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with differences in frontal brain activation in a working memory task in healthy individuals.Semantic proximity Read ↗

The impact of genome-wide supported schizophrenia risk variants in the neurogranin gene on brain structure and function.Semantic proximity Read ↗

A neuregulin 1 variant associated with abnormal cortical function and psychotic symptoms.Semantic proximity Read ↗

The effects of neuregulin1 on brain function in controls and patients with schizophrenia and bipolar disorder.Semantic proximity Read ↗

The effect of the neurogranin schizophrenia risk variant rs12807809 on brain structure and function.Semantic proximity Read ↗

Neuregulin-1 genotype is associated with structural differences in the normal human brain.Semantic proximity Read ↗

Genetic variation in the schizophrenia-risk gene neuregulin 1 correlates with brain activation and impaired speech production in a verbal fluency task in healthy individuals.Semantic proximity Read ↗

Neuregulin 1 ICE-single nucleotide polymorphism in first episode schizophrenia correlates with cerebral activation in fronto-temporal areas.Semantic proximity Read ↗

Effect of metabotropic glutamate receptor-3 variants on prefrontal brain activity in schizophrenia: An imaging genetics study using multi-channel near-infrared spectroscopy.Semantic proximity Read ↗

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia.Semantic proximity Read ↗

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.Semantic proximity Read ↗

Neural mechanisms of a genome-wide supported psychosis variant.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.