Neuregulin 1 ICE-single nucleotide polymorphism in first episode schizophrenia correlates with cerebral activation in fronto-temporal areas.

doi:10.1007/s00406-008-0837-4

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Article

Neuregulin 1 ICE-single nucleotide polymorphism in first episode schizophrenia correlates with cerebral activation in fronto-temporal areas.

European archives of psychiatry and clinical neuroscience - 1 Mar 2009

Kircher Tilo, Thienel Renate, Wagner Michael, Reske Martina, Habel Ute, Kellermann Thilo, Frommann Ingo, Schwab Sibylle, Wölwer Wolfgang, von Wilmsdorf Martina, Braus Dieter F, Schmitt Andrea, Rapp Alexander, Stöcker Tony, Shah N Jon, Henn Fritz A, Sauer Heinrich, Gaebel Wolfgang, Maier Wolfgang, Schneider Frank

Abstract excerpt

The Neuregulin (NRG1) gene has been associated with schizophrenia, but its functional implications are largely unknown. Our aim was to assess differential brain activation between patients carrying an at-risk allele on the Neuregulin 1 gene and patients without this genetic risk. Neural signal changes between 14 first episode schizophrenia patients with the at risk allele (SNP8NRG221533) from the Icelandic core...

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PMID: 18806920
DOI: 10.1007/s00406-008-0837-4

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NRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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