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Article

Wnt5b-Ryk pathway provides directional signals to regulate gastrulation movement.

The Journal of cell biology - 26 Jul 2010

Lin Shengda, Baye Lisa M, Westfall Trudi A, Slusarski Diane C

Abstract excerpt

Noncanonical Wnts are largely believed to act as permissive cues for vertebrate cell movement via Frizzled (Fz). In addition to Fz, Wnt ligands are known to regulate neurite outgrowth through an alternative receptor related to tyrosine kinase (Ryk). However, Wnt-Ryk signaling during embryogenesis is less well characterized. In this study, we report a role for Wnt5b as an instructive cue to regulate gastrulation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20660632
DOI: 10.1083/jcb.200912128
PMCID: PMC2930277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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