Article
Toxin-independent virulence of Bacillus anthracis in rabbits.
PloS one - 1 Jan 2014
Levy Haim, Glinert Itai, Weiss Shay, Sittner Assa, Schlomovitz Josef, Altboum Zeev, Kobiler David
Abstract excerpt
The accepted paradigm states that anthrax is both an invasive and toxinogenic disease and that the toxins play a major role in pathogenicity. In the guinea pig (GP) model we have previously shown that deletion of all three toxin components results in a relatively moderate attenuation in virulence, indicating that B. anthracis possesses an additional toxin-independent virulence mechanism. To characterize this...
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