Article
Differential contribution of Bacillus anthracis toxins to pathogenicity in two animal models.
Infection and immunity - 1 Aug 2012
Levy Haim, Weiss Shay, Altboum Zeev, Schlomovitz Josef, Glinert Itai, Sittner Assa, Shafferman Avigdor, Kobiler David
Abstract excerpt
The virulence of Bacillus anthracis, the causative agent of anthrax, stems from its antiphagocytic capsule, encoded by pXO2, and the tripartite toxins encoded by pXO1. The accepted paradigm states that anthrax is both an invasive and toxinogenic disease and that the toxins play major roles in pathogenicity. We tested this assumption by a systematic study of mutants with combined deletions of the pag, lef, and cya...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.