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Article

Involvement of the pagR gene of pXO2 in anthrax pathogenesis.

Scientific reports - 1 Jul 2016

Liang Xudong, Zhang Enmin, Zhang Huijuan, Wei Jianchun, Li Wei, Zhu Jin, Wang Bingxiang, Dong Shulin

Abstract excerpt

Anthrax is a disease caused by Bacillus anthracis. Specifically, the anthrax toxins and capsules encoded by the pXO1 and pXO2 plasmids, respectively, are the major virulence factors. We previously reported that the pXO1 plasmid was retained in the attenuated strain of B. anthracis vaccine strains even after subculturing at high temperatures. In the present study, we reinvestigate the attenuation mechanism of...

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Identifiers

PMID: 27363681
DOI: 10.1038/srep28827
PMCID: PMC4929452

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Source receipt: pubmed, retrieved 7 Sept 2026.

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