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Article

Vaccine protection against Bacillus cereus-mediated respiratory anthrax-like disease in mice.

Infection and immunity - 1 Mar 2013

Oh So-Young, Maier Hannah, Schroeder Jay, Richter G Stefan, Elli Derek, Musser James M, Quenee Lauriane E, Missiakas Dominique M, Schneewind Olaf

Abstract excerpt

Bacillus cereus strains harboring a pXO1-like virulence plasmid cause respiratory anthrax-like disease in humans, particularly in welders. We developed mouse models for intraperitoneal as well as aerosol challenge with spores of B. cereus G9241, harboring pBCXO1 and pBC218 virulence plasmids. Compared to wild-type B. cereus G9241, spores with a deletion of the pBCXO1-carried protective antigen gene (pagA1) were...

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Identifiers

PMID: 23319564
DOI: 10.1128/IAI.01346-12
PMCID: PMC3584855

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Source receipt: pubmed, retrieved 7 Sept 2026.

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