Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis

doi:10.1128/msystems.00291-21

Article

Direct Regulons of AtxA, the Master Virulence Regulator of Bacillus anthracis

20 Jul 2021

Abstract excerpt

Bacillus anthracis is the Gram-positive bacterial species that causes anthrax. Anthrax is still prevalent in countries mainly in Asia and Africa, where it causes economic damage and remains a public health issue. The mechanism of pathogenicity is mainly explained by the three toxin proteins expressed from the pXO1 plasmid and by proteins involved in capsule formation expressed from the pXO2 plasmid. AtxA is a...

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