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Article

Catalytically inactive anthrax toxin(s) are potential prophylactic agents.

Vaccine - 5 Dec 2007

Gupta Megha, Alam Sheeba, Bhatnagar Rakesh

Abstract excerpt

The anthrax exotoxin, which is a key mediator of anthrax related pathogenesis, is composed of two separate toxins formed by pairwise combinations of three proteins that are encoded on the pXO1 plasmid of Bacillus anthracis. Lethal toxin is composed of protective antigen (PA) combined with lethal factor (LF) while edema toxin is composed of PA and edema factor (EF). The present study found that the catalytic...

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Identifiers

PMID: 17980467
DOI: 10.1016/j.vaccine.2007.09.063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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