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Article

Comparison of study designs used to detect and characterize pharmacogenomic interactions in nonexperimental studies: a simulation study.

Pharmacogenetics and genomics - 1 Mar 2014

Avery Christy L, Der Jane S, Whitsel Eric A, Stürmer Til

Abstract excerpt

OBJECTIVES: Adverse drug reactions are common, serious, difficult to predict, and may be influenced by genetics, prompting the increasing popularity of pharmacogenomic studies. Many pharmacogenomic studies are conducted in nonexperimental settings, yet little is known about the influence of confounding by contraindication. We, therefore, compared the two designs [the overall population (OPD) and the treated-only...

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Identifiers

PMID: 24413365
DOI: 10.1097/FPC.0000000000000027
PMCID: PMC3946643

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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